Creamy Butternut Squash Lasagna Roll-Ups

Cozy, creamy, and packed with comforting flavors, these Creamy Butternut Squash Lasagna Roll-Ups are a delicious vegetarian twist on a classic. Tender lasagna noodles are rolled up with a savory butternut squash and ricotta filling, then baked in a silky béchamel sauce with gooey mozzarella on top. It’s the kind of meal that feels like a warm hug—perfect for fall, holidays, or anytime you’re craving comfort food.

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Why You’ll Love This Recipe
Cozy & Comforting – Perfect for chilly evenings or special occasions.
Vegetarian & Hearty – Satisfying without the need for meat.
Make-Ahead Friendly – Great for meal prep or entertaining.
Creamy & Flavorful – Sweet squash meets rich, cheesy goodness.
Elegant Twist – A beautiful way to present classic lasagna.

Ingredients You’ll Need

For the Filling:

• 2 cups butternut squash purée (fresh roasted or canned)
• 1 cup ricotta cheese
• ¼ cup grated Parmesan cheese
• 1 egg
• 1 tsp garlic powder
• ½ tsp salt
• ¼ tsp black pepper
• ½ tsp dried sage or thyme

For the Sauce:

• 2 tbsp butter
• 2 tbsp all-purpose flour
• 2 cups milk (whole or 2%)
• ¼ tsp nutmeg
• ½ tsp salt
• ¼ cup grated Parmesan cheese

For the Roll-Ups:

• 9–12 lasagna noodles (regular or oven-ready, cooked if needed)
• 1 cup shredded mozzarella cheese
• Chopped parsley or basil for garnish

Tools You’ll Need

• Large pot (for noodles)
• Medium saucepan (for béchamel sauce)
• 9×13 inch baking dish
• Mixing bowls
• Whisk and spatula
• Foil (for baking)

Step-by-Step Instructions

Step 1: Make the Filling

1. In a mixing bowl, combine butternut squash purée, ricotta, Parmesan, egg, garlic powder, salt, pepper, and sage.
2. Mix until smooth and well combined. Set aside.

Step 2: Cook the Lasagna Noodles
3. Boil noodles according to package instructions until al dente.
4. Drain and lay flat on parchment paper or a lightly oiled surface to prevent sticking.

Step 3: Prepare the Béchamel Sauce
5. In a saucepan, melt butter over medium heat.
6. Whisk in flour and cook for 1–2 minutes until slightly golden.
7. Gradually whisk in milk, stirring constantly to avoid lumps.
8. Add nutmeg and salt. Simmer until thickened, about 5 minutes.
9. Stir in Parmesan cheese and remove from heat.

Step 4: Assemble the Roll-Ups
10. Preheat oven to 375°F (190°C).
11. Spread ½ cup béchamel sauce on the bottom of a 9×13 inch baking dish.
12. Spread 2–3 tablespoons of the squash filling on each noodle.
13. Roll up each noodle and place seam-side down in the baking dish.
14. Pour remaining béchamel sauce over the roll-ups.
15. Sprinkle mozzarella evenly on top.

Step 5: Bake
16. Cover the dish with foil and bake for 25 minutes.
17. Remove foil and bake another 10–15 minutes until cheese is golden and bubbly.
18. Let cool for 5–10 minutes before serving.

Tips for Perfect Roll-Ups
Use Fresh Squash – Roast and purée your own for deeper flavor.
Don’t Overcook Noodles – Slightly underdone helps keep roll-ups firm.
Thin Sauce Slightly – If needed, add extra milk to the béchamel for easier spreading.
Make it Vegan – Use dairy-free ricotta and milk alternatives.
Add Greens – Mix in spinach or kale for a veggie boost.

Serving Suggestions
With a Simple Salad – Arugula, lemon vinaigrette, and shaved Parmesan.
Garlic Bread – A must for scooping up the sauce.
Roasted Veggies – Try Brussels sprouts or carrots for a fall-friendly plate.
As a Main Dish – Serve as the centerpiece of a meatless dinner.
For Holidays – A beautiful side or main for Thanksgiving or Christmas.

How to Store & Reheat

Store:
Refrigerate in an airtight container for up to 4 days.

Freeze:
Freeze assembled (but unbaked) or baked roll-ups. Wrap tightly and freeze for up to 2 months.

Reheat:
Oven – 350°F (180°C) covered, for 20–25 minutes.
Microwave – 1–2 minutes per serving, covered.

Frequently Asked Questions

1. Can I use store-bought squash purée?
Yes! Just make sure it’s 100% pure squash with no added sugar or spices.

2. What if I don’t have ricotta?
You can substitute with cottage cheese or a dairy-free ricotta alternative.

3. Can I make this ahead of time?
Absolutely—assemble and refrigerate up to 24 hours in advance before baking.

4. Is this recipe gluten-free?
Use gluten-free noodles and flour for the sauce to make it gluten-free.

Final Thoughts

These Creamy Butternut Squash Lasagna Roll-Ups are a cozy, delicious way to celebrate the season and indulge in comforting flavors—without the heaviness of traditional lasagna. With creamy squash, a rich sauce, and melty cheese, every bite is pure autumn bliss.

Make a pan, savor the moment, and don’t forget to share your creation—I’d love to see how you made this dish your own!

Preparation Time: 20 minutes
Cooking Time: 35 minutes
Cuisine: Italian-American – Comfort Food

Nutritional Information (Per Roll, 9 servings):
Calories: 280 | Protein: 12g | Carbohydrates: 28g | Fat: 13g | Fiber: 2g | Sodium: 320mg

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